Date & Time
Tuesday, July 20, 2021
202 Risk of Treatment Failure with Paliperidone Palmitate V Oral Antipsychotics in a Sample of Adults with Schizophrenia

In the U.S. utilization of long-acting injectables is relatively low (< 15%), generally initiated >10 years after diagnosis. Oral antipsychotic (OAP) nonadherence is common and leads to relapse and hospitalization. Paliperidone palmitate (PP) has demonstrated delayed time to treatment failure in adults with schizophrenia compared with OAP. This analysis evaluates PP versus OAP effects in risk of, and delaying time to, treatment failure from two studies: recent-onset schizophrenia and history of incarceration.